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Email : andrea.modica(at)inrae.fr

Tél. : +33 (0)4 32 72 29 98

Fax : +33 (0)4 32 72 29 02

INRAE

URFM - UR629

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Domaine St Paul

F - 84914 AVIGNON Cedex 9

Doctoral student at the Mediterranean Forest Ecology Research Unit, part of the Ecology and Biodiversity of Forest, Grassland and Aquatic Environments Department (ECODIV).

Andrea Modica is a doctoral student (Ecole Doctorale Aix-Marseille Université) in the BioPopEvol discipline (GEN group). His thesis focuses on the genomics of the European beech (Fagus sylvatica L.) and is entitled "Genetic bases of micro-geographical adaptation in the common beech (Fagus sylvatica L.) and modelling of its evolutionary responses to environmental gradients and climate change".

The project has three main aims:

1. estimating the genetic divergence between sub-populations of beech arranged along an altitudinal gradient (site: Mont Ventoux, FR);

2. carry out genotype x phenotype (GPA) analyses on a genome resequencing dataset in order to identify the genetic basis of various adaptive traits (sites: Mont Ventoux, FR; La Massane, FR; Pradaccio; IT);

3. use the loci identified in point (2) to help model adaptive processes on environmental gradients (site: Mont Ventoux, FR).

BIBLIOGRAPHY

Audigeos D, Brousseau L, Traissac S, Scotti-Saintagne C, Scotti I (2013). Molecular divergence in tropical tree populations occupying environmental mosaics. J Evol Biol 26: 529–544.

Cubry P, Oddou‐Muratorio S, Scotti I, Lefèvre F (2022). Interactions between microenvironment, selection and genetic architecture drive multiscale adaptation in a simulation experiment. J Evol Biol: 1–16.

Gauzere J, Klein EK, Brendel O, Davi H, Oddou-Muratorio S (2020). Microgeographic adaptation and the effect of pollen flow on the adaptive potential of a temperate tree species. New Phytol227: 641–653.

Mishra B, Ulaszewski B, Meger J, Aury J-M, Bodénès C, Lesur-Kupin I, et al. (2022). A Chromosome-Level Genome Assembly of the European Beech (Fagus sylvatica) Reveals Anomalies for Organelle DNA Integration, Repeat Content and Distribution of SNPs. Front Genet 12.

Richardson JL, Urban MC, Bolnick DI, Skelly DK (2014). Microgeographic adaptation and the spatial scale of evolution. Trends Ecol Evol 29: 165–176.

Santure AW, Garant D (2018). Wild GWAS—association mapping in natural populations. Mol Ecol Resour 18: 729–738.

Scotti I, Lalagüe H, Saintagne CS-, Ruiz R, Delphine D, Lefevre F, Cubry P, Fady B, González-Martínez S C, Roig, A, Lesur-Kupin I, Bagnoli, F, Guerin V, Ploimon C, Rozenberg P, Vendramin G G (2022). Common microgeographical selection patterns revealed in four European conifers. Mol Ecol 00: 1–19.

Yeaman S (2022). Evolution of polygenic traits under global vs local adaptation. Genetics 220: iyab134.